Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.61 |
| ▸ | PTPRC | P08575 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.61 |
| ▸ | PTPRJ | Q12913 | 1/20 | 0.61 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.61 |
| ▸ | COMT | P21964 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630786 | 0.97 | CYP1A2 (0.66) | CYP1A2HIF1AHPGDPTPN11ALOX15 | |
| SCHEMBL7630777 | 0.85 | PTPN11 (0.65) | CYP1A2HIF1AHPGDPTPN11ALOX15 | |
| SCHEMBL4461500 | 0.82 | COMT (0.64) | CYP1A2HIF1AHPGDPTPN11ALOX15 | |
| SCHEMBL28442201 | 0.81 | CYP1A2 (0.98) | CYP1A2HIF1AHPGDPTPN11ALOX15 | |
| SCHEMBL2981945 | 0.81 | COMT (0.66) | CYP1A2HIF1AHPGDPTPN11ALOX15 | |
| SCHEMBL13921609 | 0.81 | CYP1A2 (0.84) | CYP1A2HIF1AHPGDPTPN11ALOX15 | |
| SCHEMBL13936089 | 0.81 | CYP1A2 (0.73) | CYP1A2HIF1AHPGDPTPN11ALOX15 | |
| SCHEMBL13921616 | 0.81 | CYP1A2 (0.80) | CYP1A2HIF1AHPGDPTPN11ALOX15 | |
| SCHEMBL17552280 | 0.81 | CYP1A2 (0.80) | CYP1A2HIF1AHPGDPTPN11ALOX15 | |
| SCHEMBL8072742 | 0.81 | CYP1A2 (0.77) | CYP1A2HIF1AHPGDPTPN11ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002051415-A2 | USE OF SEQUESTRANTS FOR TREATING PRION DISEASES | XILINAS MICHEL (CY) | 2002-07-04 | — | — | WO | disclosed |