SCHEMBL7632110

SCHEMBL7632110

CCCCCCCCCCCCCCCCCCC(CCCCCC)C(=O)Nc1ccccc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 6/20 0.56
PLK3 Q9H4B4 3/20 0.56
CYP2C9 P11712 1/20 0.54
HPGD P15428 1/20 0.54
HDAC8 Q9BY41 5/20 0.53
HDAC3 O15379 3/20 0.53
HDAC6 Q9UBN7 3/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC2 Q92769 2/20 0.53
ALDH1A1 P00352 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
HDAC4 P56524 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
TRPA1 O75762 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7627805 1.00 PLK1 (0.56) PLK1PLK3CYP2C9HPGDHDAC8
SCHEMBL7632589 1.00 PLK1 (0.56) PLK1PLK3CYP2C9HPGDHDAC8
SCHEMBL7634493 0.78 SOAT1 (0.68) PLK1PLK3CYP2C9HPGDHDAC8
SCHEMBL7636178 0.78 SOAT1 (0.68) PLK1PLK3CYP2C9HPGDHDAC8
SCHEMBL4139016 0.78 SOAT1 (0.68) PLK1PLK3CYP2C9HPGDHDAC8
SCHEMBL5840193 0.78 SOAT1 (0.68) PLK1PLK3CYP2C9HPGDHDAC8
SCHEMBL1042215 0.78 SOAT1 (0.68) PLK1PLK3CYP2C9HPGDHDAC8
SCHEMBL2183707 0.78 SOAT1 (0.68) PLK1PLK3CYP2C9HPGDHDAC8
SCHEMBL7629650 0.78 SOAT1 (0.68) PLK1PLK3CYP2C9HPGDHDAC8
SCHEMBL3560469 0.78 SLC16A3 (0.58) PLK1PLK3ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0815871-B1 Tape plaster comprising anthranilic acid derivatives as percutaneous absorption promotors LINTEC CORP (JP) 2002-07-17 EP disclosed
EP-0815871-A1 A percutaneous absorption, a tape plaster and a method of promoting percutaneous absorption LINTEC Corporation (JP) 1998-01-07 EP disclosed
EP-0552405-A1 A percutaneous absorption promoter, a tape plaster and a method of promoting percutaneous absorption LINTEC Corporation (JP) 1993-07-28 EP disclosed