Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903392 | 0.89 | MAPT (0.56) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7070719 | 0.80 | CA12 (0.46) | KDM4EALDH1A1MAPTKMT2ARAB9A | |
| SCHEMBL6901231 | 0.80 | MAPT (0.56) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7070595 | 0.79 | MAOB (0.40) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7173515 | 0.79 | MAPT (0.58) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL6903967 | 0.79 | MAPT (0.51) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL6898972 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL6901805 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL11309411 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7177555 | 0.76 | MAPT (0.48) | KDM4EALDH1A1MAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212311-A1 | CHALCONE COUMARINS | INDENA S.p.A. (IT) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001017984-A1 | CHALCONE COUMARINS | INDENA S.P.A. (IT) | 2001-03-15 | — | — | WO | disclosed |