Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.78 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.52 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633361 | 1.00 | HDAC6 (0.78) | HDAC6HSPA5HSPA8RXFP1SLC29A1 | |
| SCHEMBL8641834 | 1.00 | HDAC6 (0.78) | HDAC6HSPA5HSPA8RXFP1SLC29A1 | |
| SCHEMBL7636281 | 1.00 | HDAC6 (0.78) | HDAC6HSPA5HSPA8RXFP1SLC29A1 | |
| SCHEMBL7801040 | 1.00 | HDAC6 (0.78) | HDAC6HSPA5HSPA8RXFP1SLC29A1 | |
| SCHEMBL7639063 | 1.00 | HDAC6 (0.78) | HDAC6HSPA5HSPA8RXFP1SLC29A1 | |
| SCHEMBL7801044 | 1.00 | HDAC6 (0.78) | HDAC6HSPA5HSPA8RXFP1SLC29A1 | |
| SCHEMBL8641831 | 1.00 | HDAC6 (0.78) | HDAC6HSPA5HSPA8RXFP1SLC29A1 | |
| SCHEMBL7801031 | 0.89 | HDAC6 (0.75) | HDAC6HSPA5HSPA8RXFP1SLC29A1 | |
| SCHEMBL7801027 | 0.89 | HDAC6 (0.75) | HDAC6HSPA5HSPA8RXFP1SLC29A1 | |
| Maribavir SCHEMBL7634149 | 0.88 | HDAC6 (1.00) | HDAC6HSPA5HSPA8RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455506-B1 | Lyxofuranosyl benzimidazoles as antiviral agents | SMITHKLINE BEECHAM CORPORATION | 2002-09-24 | — | — | US | claimed |
| EP-1000080-A1 | LYXOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | The Regents of The University of Michigan (US) | 2000-05-17 | — | — | EP | claimed |
| WO-1999006424-A1 | LYXOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-02-11 | — | — | WO | claimed |
| US-6455506-B1 | Lyxofuranosyl benzimidazoles as antiviral agents | SMITHKLINE BEECHAM CORPORATION | 2002-09-24 | — | — | US | disclosed |
| EP-1000080-A1 | LYXOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | The Regents of The University of Michigan (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006424-A1 | LYXOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-02-11 | — | — | WO | disclosed |