⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21843139 | 1.00 | — | — | |
| SCHEMBL763842 | 0.84 | — | — | |
| SCHEMBL27395611 | 0.82 | — | — | |
| SCHEMBL4012275 | 0.67 | — | — | |
| SCHEMBL50585 | 0.67 | — | — | |
| SCHEMBL50584 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL2113809 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL2114066 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL1856467 | 0.65 | — | — | |
| SCHEMBL16259887 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052643-A1 | FORMULATIONS OF CYCLOSERINE COMPOUNDS AND APPLICATIONS THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2020-03-19 | — | — | WO | disclosed |
| WO-2020052620-A1 | SALTS OF CYCLOSERINE COMPOUNDS AND APPLICATIONS THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2020-03-19 | — | — | WO | disclosed |
| WO-2017024129-A1 | COMBINATION THERAPY USING ACAMPROSATE AND D-CYCLOSERINE | CONFLUENCE PHARMACEUTICALS, LLC (US) | 2017-02-09 | — | — | WO | disclosed |
| US-8138182-B2 | Diketohydrazine derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20100087442-A1 | DIKETOHYDRAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD (JP) | 2010-04-08 | — | — | US | disclosed |