Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8951634 | 1.00 | — | — | |
| SCHEMBL723915 | 0.95 | — | — | |
| Calcium SCHEMBL9143564 | 0.91 | — | — | |
| SCHEMBL723744 | 0.86 | — | — | |
| SCHEMBL10448773 | 0.75 | TRIM24 (0.30) | TRIM24TRIM33 | |
| SCHEMBL9654975 | 0.75 | TRIM24 (0.30) | TRIM24TRIM33 | |
| SCHEMBL12659383 | 0.75 | — | — | |
| SCHEMBL7061385 | 0.75 | TRIM24 (0.42) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL10080619 | 0.75 | TRIM24 (0.42) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL19453404 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962441-B1 | Bicyclic aldehydes and ketones | GIVAUDAN SA (CH) | 2002-11-13 | — | — | EP | disclosed |
| US-6242413-B1 | ALSO 4-METHYLENESPIRO(2.6)NONANE COMPOUNDS | GIVAUDAN ROURE (INTERNATIONAL) S.A. (CH) | 2001-06-05 | — | — | US | disclosed |
| JP-2000026358-A | BICYCLIC KETONE AND ALDEHYDE | GIVAUDAN ROURE INTERNATL SA | 2000-01-25 | — | — | JP | disclosed |
| EP-0962441-A1 | Bicyclic aldehydes and ketones | Givaudan Roure (International) S.A. (CH) | 1999-12-08 | — | — | EP | disclosed |
| US-5831099-A | Compounds of 1,5-disubstituted-3,7 diaza bicyclo 3.3.0! octanes and products containing the same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1998-11-03 | — | — | US | disclosed |