Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 20/20 | 0.63 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622227 | 0.94 | LCK (0.71) | LCKFYNSRC | |
| SCHEMBL7626148 | 0.93 | LCK (0.69) | LCK | |
| SCHEMBL7629566 | 0.84 | SCD (0.59) | LCK | |
| SCHEMBL7625921 | 0.84 | LCK (0.60) | LCKFYNSRC | |
| SCHEMBL6057832 | 0.83 | LCK (0.79) | LCKFYNSRC | |
| SCHEMBL7629680 | 0.82 | LCK (0.54) | LCKFYNSRC | |
| SCHEMBL7631786 | 0.81 | LCK (0.61) | LCKFYNSRC | |
| SCHEMBL7626053 | 0.81 | LCK (0.61) | LCKFYNSRC | |
| SCHEMBL7625983 | 0.81 | LCK (0.65) | LCK | |
| SCHEMBL6058174 | 0.80 | LCK (0.66) | LCKFYNSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037632-A4 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-1037632-A1 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999024035-A1 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-05-20 | — | — | WO | disclosed |