Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.57 |
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | PPARG | P37231 | 8/20 | 0.48 |
| ▸ | MPC2 | O95563 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630978 | 0.91 | FFAR1 (0.56) | FFAR1PPARAPPARGALDH1A1NPSR1 | |
| SCHEMBL7634096 | 0.88 | FFAR1 (0.56) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| Netoglitazone SCHEMBL29355960 | 0.88 | FFAR1 (0.55) | FFAR1PPARAPPARG | |
| Netoglitazone SCHEMBL29355957 | 0.88 | FFAR1 (0.55) | FFAR1PPARAPPARG | |
| Netoglitazone SCHEMBL29361540 | 0.88 | FFAR1 (0.55) | FFAR1PPARAPPARG | |
| Netoglitazone SCHEMBL142658 | 0.88 | FFAR1 (0.55) | FFAR1PPARAPPARG | |
| Netoglitazone SCHEMBL20125595 | 0.88 | FFAR1 (0.55) | FFAR1PPARAPPARG | |
| Netoglitazone SCHEMBL29434827 | 0.88 | FFAR1 (0.55) | FFAR1PPARAPPARG | |
| Netoglitazone SCHEMBL20125596 | 0.88 | FFAR1 (0.55) | FFAR1PPARAPPARG | |
| Netoglitazone SCHEMBL8877880 | 0.87 | FFAR1 (0.54) | FFAR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186588-A1 | 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-03-13 | — | — | EP | disclosed |