Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.67 |
| ▸ | CCR8 | P51685 | 5/20 | 0.67 |
| ▸ | CCR5 | P51681 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.44 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884002 | 0.82 | SMN1; SMN2 (0.50) | CCR1CCR8CCR5L3MBTL1NPC1 | |
| SCHEMBL29563986 | 0.82 | CCR1 (1.00) | CCR1CCR8CCR5L3MBTL1NPC1 | |
| SCHEMBL31290662 | 0.82 | SMN1; SMN2 (0.50) | CCR1CCR8CCR5L3MBTL1NPC1 | |
| SCHEMBL182930 | 0.82 | CCR1 (1.00) | CCR1CCR8CCR5L3MBTL1NPC1 | |
| SCHEMBL23777914 | 0.80 | CCR1 (0.95) | CCR1CCR8CCR5L3MBTL1NPC1 | |
| SCHEMBL6744043 | 0.80 | CCR1 (0.95) | CCR1CCR8CCR5L3MBTL1NPC1 | |
| SCHEMBL30603076 | 0.80 | CCR1 (0.95) | CCR1CCR8CCR5L3MBTL1NPC1 | |
| Water SCHEMBL23927104 | 0.80 | CCR1 (0.95) | CCR1CCR8CCR5L3MBTL1NPC1 | |
| SCHEMBL4890980 | 0.80 | CCR1 (0.95) | CCR1CCR8CCR5L3MBTL1NPC1 | |
| SCHEMBL31493927 | 0.80 | CCR1 (0.95) | CCR1CCR8CCR5L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355597-B1 | SYSTEM COMPRISING EFFECTIVE AMOUNT OF PALLADIUM SOURCE AND CATALYTIC AMOUNT OF INORGANIC CO-CATALYST COMPRISING BISMUTH, CAPABLE OF INCREASING YIELD OF OR SELECTIVITY TO AROMATIC CARBONATE IN CARBONYLATION OF AROMATIC HYDROXY COMPOUND | GENERAL ELECTRIC COMPANY | 2002-03-12 | — | — | US | disclosed |