SCHEMBL7635391

SCHEMBL7635391

CC(C)Oc1cccc(CN(CC(O)C(F)(F)F)c2ccc(Oc3ccccc3)cc2)c1

nearest known ligand 0.88

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5180139 0.94 CETP (1.00) CETP
SCHEMBL7635387 0.85 CETP (0.74) CETP
SCHEMBL6136874 0.84 CETP (1.00) CETP
SCHEMBL13385264 0.84 CETP (0.87) CETP
SCHEMBL5525466 0.82 CETP (0.83) CETP
SCHEMBL5178858 0.82 CETP (1.00) CETP
SCHEMBL3278440 0.81 CETP (1.00) CETP
SCHEMBL5179220 0.81 CETP (1.00) CETP
SCHEMBL564716 0.81 CETP (1.00) CETP
SCHEMBL992314 0.81 CETP (1.00) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6458849-B1 METHOD OF TREATING OR PREVENTING A CEIP-MEDIATED DISORDER IN A SUBJECT BY ADMINISTERING A THERAPEUTICALLY EFFECTIVE AMOUNT OF A COMPOUND FOR STROKES G.D. SEARLE & CO. 2002-10-01 US disclosed