Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627624 | 0.93 | GAA (0.54) | GAAMAPTNOS3NOS1CA12 | |
| SCHEMBL7626009 | 0.87 | MAPT (0.54) | GAAMAPTNOS3NOS1CA12 | |
| SCHEMBL7627612 | 0.85 | MAPT (0.52) | GAAMAPTNOS3NOS1CA12 | |
| SCHEMBL27377737 | 0.84 | MAPT (0.54) | GAAMAPTNOS3NOS1CA12 | |
| SCHEMBL7629829 | 0.84 | MAPT (0.54) | GAAMAPTNOS3NOS1CA12 | |
| SCHEMBL7636770 | 0.84 | MAPT (0.54) | GAAMAPTNOS3NOS1CA12 | |
| SCHEMBL8382687 | 0.82 | MAPT (0.52) | GAAMAPTNOS3NOS1CA12 | |
| SCHEMBL7635744 | 0.81 | HDAC1 (0.51) | GAAMAPTNOS3NOS1CA12 | |
| SCHEMBL8383503 | 0.79 | MAPT (0.49) | GAAMAPTNOS3NOS1CA12 | |
| SCHEMBL27615690 | 0.79 | CA12 (0.48) | GAAMAPTNOS3NOS1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754683-B1 | ETHER COMPOUND, USE THEREOF, AND INTERMEDIATE FOR PRODUCING THE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-0754683-A1 | ETHER COMPOUND, USE THEREOF, AND INTERMEDIATE FOR PRODUCING THE COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-01-22 | — | — | EP | disclosed |