Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998299 | 1.00 | FFAR4 (0.42) | FFAR4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4862242 | 1.00 | FFAR4 (0.42) | FFAR4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4862250 | 1.00 | FFAR4 (0.42) | FFAR4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4862234 | 1.00 | FFAR4 (0.42) | FFAR4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13998297 | 0.89 | FFAR4 (0.43) | FFAR4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4855679 | 0.89 | FFAR4 (0.43) | FFAR4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4855742 | 0.86 | FFAR4 (0.41) | FFAR4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4852882 | 0.86 | FFAR4 (0.41) | FFAR4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4852878 | 0.86 | FFAR4 (0.41) | FFAR4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13998298 | 0.86 | FFAR4 (0.41) | FFAR4PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228024-A1 | NOVEL HYDRONAPHTALENE COMPOUNDS, PREPARED BY A RHODIUM CATALYZED RING OPENING REACTION IN THE PRESENCE OF PHOSPHINE LIGAND | AstraZeneca AB (SE) | 2002-08-07 | — | — | EP | claimed |
| WO-2001030734-A1 | NOVEL HYDRONAPHTALENE COMPOUNDS, PREPARED BY A RHODIUM CATALYZED RING OPENING REACTION IN THE PRESENCE OF PHOSPHINE LIGAND | ASTRAZENECA AB (SE) | 2001-05-03 | — | — | WO | claimed |