Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030395 | 0.83 | TSHR (0.40) | TSHRCYP3A4TDP1ATMCA2 | |
| SCHEMBL7636501 | 0.81 | TSHR (0.38) | TSHRCYP3A4TDP1ATMCA2 | |
| Maleic Acid SCHEMBL5022406 | 0.81 | TSHR (0.43) | TSHRCYP3A4TDP1ATMCA2 | |
| SCHEMBL285227 | 0.80 | TSHR (0.49) | TSHRCYP3A4TDP1ATMCA2 | |
| SCHEMBL27980321 | 0.79 | TSHR (0.40) | TSHRCYP3A4TDP1ATMCA2 | |
| SCHEMBL28119989 | 0.79 | TSHR (0.42) | TSHRCYP3A4TDP1ATMCA2 | |
| SCHEMBL6067659 | 0.79 | TSHR (0.34) | TSHRCYP2D6CYP2C19ALDH1A1GRIK1 | |
| SCHEMBL14889961 | 0.78 | TSHR (0.38) | TSHRCYP3A4TDP1ATMCA2 | |
| SCHEMBL11451456 | 0.78 | TSHR (0.45) | TSHRCYP3A4TDP1ATMCA2 | |
| SCHEMBL7754867 | 0.78 | EP300 (0.41) | TSHRATMCYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233764-A1 | TRANSDERMAL DEVICE COMPRISING A RESERVOIR AND A MATRIX CONTAINING THE SAME ACTIVE PRINCIPLE | PIERRE FABRE MEDICAMENT (FR) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001039754-A1 | TRANSDERMAL DEVICE COMPRISING A RESERVOIR AND A MATRIX CONTAINING THE SAME ACTIVE PRINCIPLE | PIERRE FABRE MEDICAMENT (FR) | 2001-06-07 | — | — | WO | disclosed |
| US-5565130-A | ACRYLATED POLYBUTADIENE WITH BOTH VINYL AND 1,4-ADDITION UNITS COPOLYMERIZED WITH ACRYLATE MONOMERS | ROHM GMBH CHEMISCHE FABRIK (DE) | 1996-10-15 | — | — | US | disclosed |