Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635730 | 1.00 | CACNA1C (0.34) | CACNA1CPTGS1ESR1PDE4ACHEK1 | |
| SCHEMBL7635380 | 0.84 | — | — | |
| SCHEMBL7636379 | 0.79 | KDM4E (0.41) | PTGS1ESR1CHEK1LIMK1DYRK1A | |
| SCHEMBL7983393 | 0.79 | CACNA1C (0.39) | CACNA1CPTGS1ESR1PDE4AABCC2 | |
| SCHEMBL7983370 | 0.79 | CACNA1C (0.39) | CACNA1CPTGS1ESR1PDE4AABCC2 | |
| SCHEMBL7635372 | 0.77 | CACNA1C (0.34) | CACNA1CPTGS1ESR1PDE4AMEN1 | |
| SCHEMBL7634714 | 0.76 | CACNA1C (0.36) | CACNA1CPTGS1ESR1PDE4AMEN1 | |
| SCHEMBL7637314 | 0.76 | CACNA1C (0.36) | CACNA1CPTGS1ESR1PDE4AMEN1 | |
| SCHEMBL7630479 | 0.76 | CACNA1C (0.34) | CACNA1CPTGS1ESR1PDE4AMEN1 | |
| SCHEMBL7628267 | 0.73 | IDO1 (0.36) | CACNA1CPTGS1ESR1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022279-B1 | NEW CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2002-09-04 | — | — | EP | disclosed |