Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3120557 | 0.89 | ELANE (0.51) | ELANEHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL11689807 | 0.85 | KDM4E (0.62) | ELANEHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL5506361 | 0.84 | KDM4E (0.57) | ELANEHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL4621853 | 0.83 | HPGD (0.66) | ELANEHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL207636 | 0.83 | ELANE (0.50) | ELANEHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL29497591 | 0.83 | ELANE (0.50) | ELANEHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL29670258 | 0.82 | ELANE (0.64) | ELANEHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL474811 | 0.82 | ELANE (0.64) | ELANEHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL5492392 | 0.82 | HPGD (0.64) | ELANEHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL30400135 | 0.82 | HPGD (0.64) | ELANEHPGDHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869138-B1 | NOVEL COPOLYMERS FORMED FROM THREE COMPONENTS AND INTRAOCULAR LENSES MADE THEREOF | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-08-07 | — | — | EP | claimed |
| US-6268511-B1 | USED FOR PRODUCING COPOLYMER WITH ACRYLIC ESTER COMONOMERS; COPOLYMERS ARE USED FOR FOLDABLE INTRAOCULAR LENSES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-0987247-A1 | ITACONATE DERIVATIVES USED FOR A COMPONENT OF A POLYMER | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |