Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635068 | 0.79 | — | — | |
| SCHEMBL1418560 | 0.78 | ANPEP (0.43) | ANPEPTSHRLMNATHRBADRB2 | |
| SCHEMBL1582226 | 0.75 | ANPEP (0.41) | ANPEPTSHRLMNATHRB | |
| SCHEMBL1017192 | 0.73 | ANPEP (0.39) | ANPEPTSHRLMNATHRBADRB2 | |
| SCHEMBL4261185 | 0.73 | ANPEP (0.39) | ANPEPTSHRLMNATHRBADRB2 | |
| SCHEMBL18007369 | 0.69 | TSHR (0.39) | ANPEPTSHRLMNATHRBALDH1A1 | |
| SCHEMBL5487541 | 0.69 | ANPEP (0.55) | ANPEPTSHRLMNATHRBPCSK9 | |
| SCHEMBL20495947 | 0.68 | ANPEP (0.35) | ANPEPTSHRLMNAALDH1A1 | |
| SCHEMBL1237 | 0.67 | ANPEP (0.53) | ANPEPTSHRLMNATHRBPCSK9 | |
| SCHEMBL10899969 | 0.67 | ANPEP (0.53) | ANPEPTSHRLMNATHRBPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353071-B1 | DESICCATING MIXTURE OF ALUMINOXANE AND SOLVENT TO PRODUCE SOLID, MIXING WITH SOLVENT, CONTACTING SECOND MIXTURE WITH INSOLUBLIZATION AGENT TO PRODUCE ALUMINOXANE COMPOSITION, COMBINING WITH TRANSITION METAL CATALYST, POLYMERIZING OLEFIN | PHILLIPS PETROLEUM COMPANY | 2002-03-05 | — | — | US | claimed |
| US-6096915-A | Processes to produce organo-aluminoxane compositions | PALACKAL SYRIAC J (US) | 2000-08-01 | — | — | US | claimed |
| US-6417302-B1 | REACTION PRODUCT OF DI(PENTAFLUOROPHENYL) BORINIC ACID AND ORGANOALUMINUM COMPOUND; OLEFIN POLYMERIZATION COORDINATION CATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2002-07-09 | — | — | US | disclosed |
| US-6353071-B1 | DESICCATING MIXTURE OF ALUMINOXANE AND SOLVENT TO PRODUCE SOLID, MIXING WITH SOLVENT, CONTACTING SECOND MIXTURE WITH INSOLUBLIZATION AGENT TO PRODUCE ALUMINOXANE COMPOSITION, COMBINING WITH TRANSITION METAL CATALYST, POLYMERIZING OLEFIN | PHILLIPS PETROLEUM COMPANY | 2002-03-05 | — | — | US | disclosed |
| EP-0812860-B1 | Processes to produce organo-aluminoxane compositions | PHILLIPS PETROLEUM CO (US) | 2000-08-30 | — | — | EP | disclosed |
| US-6096915-A | Processes to produce organo-aluminoxane compositions | PALACKAL SYRIAC J (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0812860-A1 | Processes to produce organo-aluminoxane compositions | PHILLIPS PETROLEUM COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5583189-A | USING A CATALYST SYSTEM COMPRISING THE REACTION PRODUCT OF A METALLOCENE COMPOUND, A SOLID ORGANOALUMINOXY PRODUCT AND AN ORGANOMETAL COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| US-5496781-A | OLEFIN POLYMERIZATION | PHILLIPS PETROLEUM COMPANY (US) | 1996-03-05 | — | — | US | disclosed |
| US-5480848-A | CONTAINING METALLOCENE AND REACTION PRODUCT OF ACIDIC HYDROGEN FREE ORGANIC BORANE AND ORGANOALUMINOXANE; ANTIFOULING, BROAD MOLECULAR WEIGHT DISTRIBUTION; POLYETTHYLENE | PHILLIPS PETROLEUM COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0683179-A1 | Metallocene catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-11-22 | — | — | EP | disclosed |
| US-5416179-A | Metallocene, isobutene | PHILLIPS PETROLEUM COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0630900-A1 | Organo-aluminoxy product and use | PHILLIPS PETROLEUM COMPANY (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5354721-A | Organo-aluminoxy product and use | PHILLIPS PETROLEUM COMPANY (US) | 1994-10-11 | — | — | US | disclosed |