SCHEMBL763855 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	HRH1	P35367	11/20	0.40

▸	CYP2D6	P10635	9/20	0.40

▸	KCNH2	Q12809	8/20	0.38

▸	CHRM1	P11229	3/20	0.38

▸	PROKR1	Q8TCW9	1/20	0.36

▸	MAPT	P10636	2/20	0.36

▸	TP53	P04637	1/20	0.36

▸	AGTR1	P30556	2/20	0.36

▸	AGTR2	P50052	2/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL763858	0.92	KCNH2 (0.42)	HRH1CYP2D6KCNH2CHRM1AGTR1
SCHEMBL742614	0.90	HRH1 (0.40)	HRH1CYP2D6KCNH2CHRM1TP53
SCHEMBL742613	0.90	HRH1 (0.40)	HRH1CYP2D6KCNH2CHRM1TP53
SCHEMBL16301236	0.90	KCNH2 (0.47)	HRH1CYP2D6KCNH2CHRM1MAPT
SCHEMBL16301237	0.90	HRH1 (0.40)	HRH1CYP2D6KCNH2CHRM1PROKR1
SCHEMBL763838	0.90	HRH1 (0.40)	HRH1CYP2D6KCNH2CHRM1MAPT
SCHEMBL763924	0.90	HRH1 (0.41)	HRH1CYP2D6KCNH2CHRM1AGTR1
SCHEMBL10292639	0.90	HRH1 (0.39)	HRH1CYP2D6KCNH2CHRM1AGTR1
SCHEMBL739547	0.89	HRH1 (0.41)	HRH1CYP2D6KCNH2CHRM1
SCHEMBL739548	0.89	HRH1 (0.41)	HRH1CYP2D6KCNH2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8138168-B1	Renin inhibitors	TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP)	2012-03-20	—	—	US	disclosed