Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735226 | 0.89 | AURKA (1.00) | AURKAAURKB | |
| SCHEMBL759106 | 0.89 | AURKA (0.81) | AURKAAURKB | |
| SCHEMBL10063835 | 0.86 | AURKA (0.81) | AURKAAURKB | |
| SCHEMBL757544 | 0.85 | AURKA (0.91) | AURKAAURKB | |
| SCHEMBL759105 | 0.85 | AURKA (0.91) | AURKAAURKB | |
| SCHEMBL759001 | 0.84 | AURKA (0.90) | AURKAAURKB | |
| SCHEMBL759075 | 0.84 | AURKA (0.89) | AURKAAURKB | |
| SCHEMBL759107 | 0.84 | AURKA (1.00) | AURKAAURKB | |
| SCHEMBL758936 | 0.84 | AURKA (0.89) | AURKAAURKB | |
| SCHEMBL759148 | 0.84 | AURKA (0.89) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138194-B2 | Fused bicyclic pyrimidine compounds as aurora kinase inhibitors | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2012-03-20 | — | — | US | disclosed |
| US-20090275533-A1 | FUSED BICYCLIC PYRIMIDINE COMPOUNDS AS AURORA KINASE INHIBITORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275533-A1 | FUSED BICYCLIC PYRIMIDINE COMPOUNDS AS AURORA KINASE INHIBITORS | AURKB, AURKA, AURKC | AURKA 2/4885AURKB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.