Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 8/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.32 |
| ▸ | TUBB | P07437 | 3/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL763401 | 0.93 | MEN1 (0.41) | MEN1KMT2AACVR1TGFBR1HTR1A | |
| SCHEMBL764515 | 0.93 | MEN1 (0.41) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL763877 | 0.92 | MEN1 (0.40) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL764918 | 0.91 | MEN1 (0.40) | MEN1KMT2AACVR1TGFBR1TUBB4A | |
| SCHEMBL10042008 | 0.86 | MEN1 (0.43) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL10041941 | 0.85 | MEN1 (0.43) | MEN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL10041985 | 0.84 | MEN1 (0.42) | MEN1KMT2AACVR1TGFBR1MDM2 | |
| SCHEMBL739307 | 0.79 | TLR9 (0.41) | MEN1KMT2AACVR1TGFBR1HTR1A | |
| SCHEMBL740425 | 0.79 | TLR9 (0.41) | MEN1KMT2AACVR1TGFBR1HTR1A | |
| SCHEMBL740385 | 0.78 | TLR9 (0.42) | MEN1KMT2AACVR1TGFBR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138184-B2 | Isoxazole derivatives and pharmaceutical compositions comprising the same | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-03-20 | — | — | US | disclosed |
| US-20090215768-A1 | ISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215768-A1 | ISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | TBXA2R, F12, PTH1R | MEN1 563/4885KMT2A 2590/4885ACVR1 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.