Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.77 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.70 |
| ▸ | PYGL | P06737 | 13/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888212 | 0.99 | SMYD3 (0.79) | SMYD3MLLT1PYGLHRH4HRH3 | |
| SCHEMBL30578672 | 0.88 | SMYD3 (0.76) | SMYD3MLLT1PYGLHRH4HRH3 | |
| SCHEMBL19710296 | 0.87 | SMYD3 (1.00) | SMYD3MLLT1PYGLHRH4HRH3 | |
| SCHEMBL21489923 | 0.87 | SMYD3 (1.00) | SMYD3MLLT1PYGLHRH4HRH3 | |
| SCHEMBL12101155 | 0.86 | SMYD3 (0.76) | SMYD3MLLT1PYGLHRH4HRH3 | |
| SCHEMBL12670484 | 0.85 | SMYD3 (0.74) | SMYD3MLLT1PYGLHRH4HRH3 | |
| SCHEMBL11960283 | 0.85 | SMYD3 (0.74) | SMYD3MLLT1PYGLHRH4HRH3 | |
| SCHEMBL4363306 | 0.85 | SMYD3 (0.63) | SMYD3MLLT1PYGLF7F3 | |
| SCHEMBL4360293 | 0.85 | SMYD3 (0.63) | SMYD3MLLT1PYGLF7F3 | |
| SCHEMBL4360291 | 0.85 | SMYD3 (0.63) | SMYD3MLLT1PYGLF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577301-B1 | Antithrombotic diaminocyclohexane derivatives | DAIICHI SANKYO CO LTD (JP) | 2012-09-12 | — | — | EP | disclosed |
| EP-1405852-B1 | DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2012-08-01 | — | — | EP | disclosed |
| EP-1270557-B1 | ETHYLENEDIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-2343290-A1 | Diamine derivatives as factor X inhibitors | Daiichi Sankyo Company, Limited (JP) | 2011-07-13 | — | — | EP | disclosed |