Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13672053 | 1.00 | BTK (0.44) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL3338665 | 1.00 | BTK (0.44) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL3338661 | 1.00 | BTK (0.44) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL715488 | 1.00 | BTK (0.44) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL3586608 | 1.00 | BTK (0.44) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL4463947 | 1.00 | BTK (0.44) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL1503772 | 1.00 | BTK (0.44) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL30473186 | 1.00 | BTK (0.44) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL28451571 | 0.88 | BTK (0.44) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL31009025 | 0.88 | BTK (0.44) | BTKKDM1AMAOBNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |