Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28767867 | 1.00 | HMGCR (0.52) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL818663 | 0.94 | HMGCR (0.54) | HMGCRNR1I2GAAKMT2AMEN1 | |
| Alcohol SCHEMBL29989701 | 0.92 | HMGCR (0.54) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL5709912 | 0.92 | HMGCR (0.52) | HMGCRNR1I2GAAKMT2AMEN1 | |
| Magnesium SCHEMBL4347217 | 0.92 | HMGCR (0.52) | HMGCRNR1I2GAAKMT2AMEN1 | |
| Alcohol SCHEMBL28135113 | 0.91 | HMGCR (0.52) | HMGCRNR1I2GAAKMT2AMEN1 | |
| Phenol SCHEMBL29285406 | 0.85 | GAA (0.56) | HMGCRNR1I2GAAKMT2AMEN1 | |
| Monoethanolamine SCHEMBL31606847 | 0.85 | HMGCR (0.47) | HMGCRNR1I2GAAKMT2AMEN1 | |
| Butyl Alcohol SCHEMBL7529227 | 0.85 | HMGCR (0.47) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL3164392 | 0.84 | HMGCR (0.55) | HMGCRNR1I2GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795243-B2 | End group functionalization agents for polydiene | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-20210171672-A1 | END GROUP FUNCTIONALIZATION AGENTS FOR POLYDIENE | UNIV IOWA STATE RES FOUND INC (US) | 2021-06-10 | — | — | US | disclosed |
| US-10919989-B2 | End group functionalization agents for polydiene | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-02-16 | — | — | US | disclosed |
| US-20190119409-A1 | END GROUP FUNCTIONALIZATION AGENTS FOR POLYDIENE | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-04-25 | — | — | US | disclosed |
| US-9856337-B2 | Polymerization catalysts | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-01-02 | — | — | US | disclosed |
| US-20170275402-A1 | POLYMERIZATION CATALYSTS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2017-09-28 | — | — | US | disclosed |
| EP-0856526-B1 | OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME | CHISSO CORP (JP) | 2002-08-28 | — | — | EP | disclosed |
| US-6313225-B2 | High melt tension, high crystallization temperature; hollow moldings | CHISSO CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| US-20010004657-A1 | OLEFIN(CO-) POLYMER COMPOSITIONS AND METHOD FOR PRODUCING THE SAME ANDCATALYST FOR OLEFIN (CO-) POLYMERIZATION AND METHOD FOR PRODUCING THE SAME | CHISSO CORPORATION (JP) | 2001-06-21 | — | — | US | disclosed |
| US-6156845-A | Polyolefin composition and method of making | CHISSO CORPORATION (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0856526-A1 | OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME | CHISSO CORPORATION (JP) | 1998-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275402-A1 | POLYMERIZATION CATALYSTS | SIK2, SIK3, SGK2 | HMGCR 1280/4885NR1I2 1730/4885GAA 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.