Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3549857 | 1.00 | HDAC6 (0.70) | HDAC6SLC29A1ADORA2AADORA2BADORA3 | |
| SCHEMBL7632989 | 1.00 | HDAC6 (0.70) | HDAC6SLC29A1ADORA2AADORA2BADORA3 | |
| SCHEMBL7633291 | 1.00 | HDAC6 (0.70) | HDAC6SLC29A1ADORA2AADORA2BADORA3 | |
| SCHEMBL7632995 | 1.00 | HDAC6 (0.70) | HDAC6SLC29A1ADORA2AADORA2BADORA3 | |
| SCHEMBL5110006 | 1.00 | HDAC6 (0.70) | HDAC6SLC29A1ADORA2AADORA2BADORA3 | |
| SCHEMBL5110015 | 1.00 | HDAC6 (0.70) | HDAC6SLC29A1ADORA2AADORA2BADORA3 | |
| SCHEMBL3549859 | 1.00 | HDAC6 (0.70) | HDAC6SLC29A1ADORA2AADORA2BADORA3 | |
| SCHEMBL5110010 | 1.00 | HDAC6 (0.70) | HDAC6SLC29A1ADORA2AADORA2BADORA3 | |
| SCHEMBL7801038 | 0.96 | HDAC6 (0.71) | HDAC6SLC29A1ADORA2AADORA2BADORA3 | |
| SCHEMBL7801036 | 0.96 | HDAC6 (0.71) | HDAC6SLC29A1ADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455506-B1 | Lyxofuranosyl benzimidazoles as antiviral agents | SMITHKLINE BEECHAM CORPORATION | 2002-09-24 | — | — | US | claimed |
| EP-1000080-A1 | LYXOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | The Regents of The University of Michigan (US) | 2000-05-17 | — | — | EP | claimed |
| WO-1999006424-A1 | LYXOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-02-11 | — | — | WO | claimed |
| US-6455506-B1 | Lyxofuranosyl benzimidazoles as antiviral agents | SMITHKLINE BEECHAM CORPORATION | 2002-09-24 | — | — | US | disclosed |
| EP-1000080-A1 | LYXOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | The Regents of The University of Michigan (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006424-A1 | LYXOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-02-11 | — | — | WO | disclosed |