Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.67 |
| ▸ | HTR2A | P28223 | 7/20 | 0.67 |
| ▸ | HTR2B | P41595 | 6/20 | 0.67 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | HTR1D | P28221 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | HTR1B | P28222 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
| ▸ | HTR1F | P30939 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978983 | 0.87 | HTR2C (0.54) | HTR2CHTR2AHTR2BHTR1ACYP2D6 | |
| SCHEMBL11096774 | 0.84 | HTR2A (0.67) | HTR2CHTR2AHTR2BHTR1ACYP2D6 | |
| SCHEMBL1120490 | 0.84 | HTR2A (0.67) | HTR2CHTR2AHTR2BHTR1ACYP2D6 | |
| SCHEMBL6469548 | 0.83 | HTR2C (0.60) | HTR2CHTR2AHTR2BHTR1ACYP2D6 | |
| SCHEMBL12352693 | 0.83 | TRPV1 (0.55) | HTR2CHTR2AHTR2BHTR1ACYP2D6 | |
| SCHEMBL6516528 | 0.83 | HTR2C (0.55) | HTR2CHTR2AHTR2BHTR1ACYP2D6 | |
| SCHEMBL29414816 | 0.83 | HTR2C (0.55) | HTR2CHTR2AHTR2BHTR1ACYP2D6 | |
| SCHEMBL10758547 | 0.83 | HTR2A (0.65) | HTR2CHTR2AHTR2BSLC6A4 | |
| SCHEMBL1247512 | 0.83 | HTR2A (0.65) | HTR2CHTR2AHTR2BSLC6A4KMT2A | |
| SCHEMBL5232490 | 0.83 | HTR2A (0.65) | HTR2CHTR2AHTR2BHTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020173511-A1 | Serotonergic compositions and methods for treatment of mild cognitive impairment | WURTMAN RICHARD J (US) | 2002-11-21 | — | — | US | disclosed |