Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | AGL | P35573 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | LCT | P09848 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801872 | 0.90 | MAPK1 (0.44) | MAPK1KCNH2KCNJ1ALDH1A1SIGMAR1 | |
| SCHEMBL9801966 | 0.90 | MAPK1 (0.47) | MAPK1KCNH2KCNJ1KDM4EALDH1A1 | |
| SCHEMBL13550395 | 0.90 | MAPK1 (0.44) | MAPK1KCNH2KCNJ1SIGMAR1CYP2D6 | |
| SCHEMBL9801391 | 0.89 | MAPK1 (0.50) | MAPK1KCNH2KCNJ1KDM4EALDH1A1 | |
| SCHEMBL9801234 | 0.88 | MAPK1 (0.49) | MAPK1KCNH2KCNJ1KDM4EALDH1A1 | |
| SCHEMBL9801539 | 0.86 | MAPK1 (0.48) | MAPK1KCNH2KCNJ1KDM4EALDH1A1 | |
| SCHEMBL9801366 | 0.84 | MAPK1 (0.41) | MAPK1KCNH2KCNJ1ALDH1A1SIGMAR1 | |
| SCHEMBL9801048 | 0.82 | MAPK1 (0.38) | MAPK1KCNH2KCNJ1SIGMAR1OPRL1 | |
| SCHEMBL15312557 | 0.81 | MAPK1 (0.53) | MAPK1KCNH2KDM4EALDH1A1CYP2C19 | |
| SCHEMBL9939558 | 0.81 | MAPK1 (0.53) | MAPK1KCNH2KDM4EALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128421-A1 | Curable compositions | SHELVEY MICHAEL FRANCIS (GB) | 2002-09-12 | — | — | US | claimed |
| US-7217447-B2 | Ink-jet recording sheet | FUJIFILM CORPORATION (JP) | 2007-05-15 | — | — | US | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| US-4754036-A | Conjoint production of C-methyl triethylene diamine and allyl piperazine | TEXACO INC. (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0197613-A2 | Water addition to enhance phosphoric acid salt catalyst activity | UNION CARBIDE CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0058430-B1 | DYESTUFF-CONTAINING MICROSCOPIC CAPSULE DISPERSION FOR RECORD MATERIALS | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-12-04 | — | — | EP | disclosed |
| US-4384871-A | Dyestuff-containing microscopic capsule dispersion for record materials | MITSUI TOATSU CHEMICALS, INC. (JP) | 1983-05-24 | — | — | US | disclosed |
| EP-0058430-A1 | Dyestuff-containing microscopic capsule dispersion for record materials | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-08-25 | — | — | EP | disclosed |
| US-4092316-A | Synthesis of C-alkyl-triethylenediamines | TEXACO DEVELOPMENT CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |