SCHEMBL764293

SCHEMBL764293

CCc1c(C)c(OCCCS(C)(=O)=O)c(Cl)c(CC)c1-c1cccc(CO)c1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL206790 0.94 FFAR1 (0.46) FFAR1
SCHEMBL530076 0.86 FFAR1 (0.56) FFAR1
SCHEMBL206805 0.84 FFAR1 (0.55) FFAR1
SCHEMBL15800609 0.81 FFAR1 (0.51) FFAR1
SCHEMBL204587 0.76 FFAR1 (0.56) FFAR1
SCHEMBL16552665 0.76 FFAR1 (0.47) FFAR1
SCHEMBL203930 0.75 FFAR1 (0.69) FFAR1
SCHEMBL13068052 0.73 FFAR1 (0.55) FFAR1
SCHEMBL204438 0.72 FFAR1 (0.58) FFAR1
SCHEMBL15800616 0.71 FFAR1 (0.60) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2431367-A2 Fused cyclic compounds as GPR40 receptor modulators Takeda Pharmaceutical Company Limited (JP) 2012-03-21 EP disclosed