Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176505 | 0.89 | NPC1 (0.44) | ESRRGMAOBMAOAALDH1A1CYP3A4 | |
| SCHEMBL13532752 | 0.81 | NPC1 (0.56) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL17917284 | 0.81 | NPC1 (0.40) | CA1CA2ALDH1A1NPC1RAB9A | |
| SCHEMBL10210911 | 0.80 | IDO1 (0.46) | MAOBALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL15980927 | 0.79 | GRIA4 (0.53) | ESRRGCA1CA2ALDH1A1NPC1 | |
| SCHEMBL8261416 | 0.79 | TAAR1 (0.61) | ALDH1A1 | |
| SCHEMBL10246680 | 0.79 | TMEM97 (0.61) | ESRRGCA2ALDH1A1CYP3A4ADRB2 | |
| SCHEMBL13900372 | 0.79 | TAAR1 (0.61) | GFERALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1640060 | 0.78 | ATM (0.58) | MAOBMAOAALDH1A1CYP3A4TSHR | |
| SCHEMBL6615523 | 0.78 | EPHX2 (0.46) | GFERMAOBMAOACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-0854867-B1 | TETRAHYDROQUINOLINES AS NMDA ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 2002-07-31 | — | — | EP | disclosed |
| US-5977136-A | Tetrahydroquinolines as NMDA antagonists | GLAXO WELLCOME SPA (IT) | 1999-11-02 | — | — | US | disclosed |
| EP-0854867-A1 | TETRAHYDROQUINOLINES AS NMDA ANTAGONISTS | GLAXO WELLCOME S.p.A. (IT) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997012870-A1 | TETRAHYDROQUINOLINES AS NMDA ANTAGONISTS | GLAXO WELLCOME S.P.A. (IT) | 1997-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | GFER 3990/4885ESRRG 3944/4885MAOB 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.