Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831188 | 0.98 | KDM4E (0.69) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL2094838 | 0.86 | KDM4E (0.66) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11928962 | 0.85 | CHRM2 (0.72) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3161038 | 0.85 | MEN1 (0.82) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8401996 | 0.84 | CYP1A2 (0.76) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL30087523 | 0.84 | APOBEC3A (0.73) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8392131 | 0.83 | MEN1 (0.58) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4001895 | 0.83 | MEN1 (0.73) | KDM4EMEN1KMT2AALDH1A1BCHE | |
| SCHEMBL13284339 | 0.83 | MEN1 (0.79) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4159488 | 0.83 | MEN1 (0.65) | KDM4EMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192134-A2 | PROCESSES FOR THE PREPARATION OF (R)-G(A)-(2,3-DIMETHOXYPHENYL)-1-(2-(4-FLUOROPHENYL)ETHYL)-4-PIPERIDINEMETHANOL | Aventis Pharmaceuticals Inc. (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-1999046245-A2 | PROCESSES FOR THE PREPARATION OF (R)-α- (2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-16 | — | — | WO | disclosed |