Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.61 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | TOP1 | P11387 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643975 | 1.00 | EP300 (0.61) | EP300GABRR1TERTPTPN1PPARG | |
| SCHEMBL16288157 | 0.98 | EP300 (0.64) | EP300GABRR1TERTPTPN1PPARG | |
| SCHEMBL6138616 | 0.98 | EP300 (0.64) | EP300GABRR1TERTPTPN1PPARG | |
| SCHEMBL16288159 | 0.98 | EP300 (0.64) | EP300GABRR1TERTPTPN1PPARG | |
| SCHEMBL8948205 | 0.98 | EP300 (0.64) | EP300GABRR1TERTPTPN1PPARG | |
| SCHEMBL27969347 | 0.98 | EP300 (0.64) | EP300GABRR1TERTPTPN1PPARG | |
| SCHEMBL6924911 | 0.98 | EP300 (0.64) | EP300GABRR1TERTPTPN1PPARG | |
| SCHEMBL16288161 | 0.98 | EP300 (0.64) | EP300GABRR1TERTPTPN1PPARG | |
| SCHEMBL8948204 | 0.98 | EP300 (0.64) | EP300GABRR1TERTPTPN1PPARG | |
| SCHEMBL27963404 | 0.98 | EP300 (0.64) | EP300GABRR1TERTPTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811593-B1 | 1,4-diaryl-2-fluoro-2-butene insecticidal and acaricidal agents | BASF AG (DE) | 2002-07-24 | — | — | EP | disclosed |
| US-6235754-B1 | USING 1,4-DIARYL-(2-FLUORO- OR 2,3-DIFLUORO-)-2-BUTENE | AMERICAN CYANAMID COMPANY | 2001-05-22 | — | — | US | disclosed |
| US-5998673-A | ENANTIOMORPHS; BROMINATION 4-ARYL-3-FLUORO-2-BUTEN-1-OL; REACTING WITH ARYLBORONIC ACID IN PRESENCE OF A CATALYST | AMERICAN CYANAMID COMPANY (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0933027-A1 | Methods and compositions for protecting animals and humans against attack and infestation by arthropod and helminth parasites | American Cyanamid Company (US) | 1999-08-04 | — | — | EP | disclosed |
| US-5849958-A | 1,4,diaryl-2-fluoro-2-butene insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0811593-A1 | 1,4-diaryl-2-fluoro-2-butene insecticidal and acaricidal agents | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |