Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGH | Q92820 | 2/20 | 0.58 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | CPA2 | P48052 | 1/20 | 0.40 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5060655 | 0.86 | GGH (0.59) | GGHNAALAD2GAAMMP9MMP8 | |
| SCHEMBL5054703 | 0.85 | GGH (0.58) | GGHNAALAD2GAAMMP9MMP8 | |
| SCHEMBL5054386 | 0.84 | GGH (0.54) | GGHNAALAD2GAAALDH1A1HPGD | |
| SCHEMBL5053094 | 0.82 | GGH (0.55) | GGHNAALAD2CPA1TDP1FOLH1 | |
| SCHEMBL1374225 | 0.82 | GGH (0.65) | GGHNAALAD2GAAMMP9MMP8 | |
| SCHEMBL1374224 | 0.82 | GGH (0.65) | GGHNAALAD2GAAMMP9MMP8 | |
| SCHEMBL5052861 | 0.79 | GGH (0.54) | GGHNAALAD2FOLH1 | |
| SCHEMBL7608038 | 0.78 | GGH (0.53) | GGHMMP9L3MBTL1LMNA | |
| SCHEMBL5057948 | 0.78 | GGH (0.52) | GGHNAALAD2CPA1CPA2CPA4 | |
| SCHEMBL23881911 | 0.77 | ERAP1 (0.42) | GGHALDH1A1HPGDFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413948-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | GUILFORD PHARMACEUTICALS INC. | 2002-07-02 | — | — | US | disclosed |