SCHEMBL7645562

SCHEMBL7645562

CCc1cc(Oc2cccc(N(Cc3ccccc3OC(F)(F)F)CC(O)C(C)C)c2)ccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6313501 0.90 CETP (0.62) CETP
SCHEMBL6306220 0.87 CETP (0.60) CETP
SCHEMBL6392550 0.87 CETP (0.82) CETP
SCHEMBL6312347 0.86 CETP (0.58) CETP
SCHEMBL6308353 0.85 CETP (0.56) CETP
SCHEMBL6304185 0.82 CETP (0.82) CETP
SCHEMBL6306804 0.82 CETP (0.82) CETP
SCHEMBL6312013 0.82 CETP (0.82) CETP
SCHEMBL6305393 0.81 CETP (0.84) CETP
SCHEMBL6308349 0.79 CETP (0.63) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6482862-B1 Method of using substituted N-benzyl-N-phenyl aminoalcohols for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. 2002-11-19 US claimed