Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | CD40 | P25942 | 1/20 | 0.37 |
| ▸ | CD40LG | P29965 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529846 | 0.89 | APP (0.47) | ALDH1A1KDM4ETSHRL3MBTL1LMNA | |
| SCHEMBL7529853 | 0.89 | APP (0.47) | ALDH1A1KDM4ETSHRL3MBTL1LMNA | |
| SCHEMBL7528977 | 0.88 | PTPN1 (0.41) | ALDH1A1KDM4ETSHRL3MBTL1LMNA | |
| SCHEMBL7528984 | 0.88 | PTPN1 (0.41) | ALDH1A1KDM4ETSHRL3MBTL1LMNA | |
| SCHEMBL7528550 | 0.88 | KDM4E (0.51) | ALDH1A1KDM4EL3MBTL1LMNAMEN1 | |
| SCHEMBL7527005 | 0.88 | KDM4E (0.51) | ALDH1A1KDM4EL3MBTL1LMNAMEN1 | |
| SCHEMBL7527657 | 0.88 | TSHR (0.50) | ALDH1A1KDM4ETSHRL3MBTL1LMNA | |
| SCHEMBL7527663 | 0.88 | TSHR (0.50) | ALDH1A1KDM4ETSHRL3MBTL1LMNA | |
| SCHEMBL7648628 | 0.84 | APP (0.46) | ALDH1A1KDM4ETSHRHSD17B10PTPN1 | |
| SCHEMBL7648625 | 0.84 | APP (0.46) | ALDH1A1KDM4ETSHRHSD17B10PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |