Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.80 |
| ▸ | DPP7 | Q9UHL4 | 13/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12284256 | 1.00 | DPP4 (0.80) | DPP4CYP2D6DPP7DPP9KCNH2 | |
| SCHEMBL12284230 | 0.89 | DPP4 (1.00) | DPP4CYP2D6DPP7DPP9KCNH2 | |
| SCHEMBL21067472 | 0.89 | DPP4 (1.00) | DPP4CYP2D6DPP7DPP9KCNH2 | |
| SCHEMBL8243254 | 0.89 | DPP4 (1.00) | DPP4CYP2D6DPP7DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL2417341 | 0.88 | DPP4 (1.00) | DPP4CYP2D6DPP7DPP9KCNH2 | |
| SCHEMBL13703651 | 0.87 | DPP4 (0.60) | DPP4CYP2D6DPP7DPP9KCNH2 | |
| SCHEMBL764705 | 0.86 | DPP4 (0.59) | DPP4CYP2D6DPP7DPP9KCNH2 | |
| SCHEMBL12284444 | 0.83 | DPP4 (0.56) | DPP4CYP2D6DPP7DPP9KCNH2 | |
| SCHEMBL8246266 | 0.83 | DPP4 (0.56) | DPP4CYP2D6DPP7DPP9KCNH2 | |
| SCHEMBL8244465 | 0.82 | DPP4 (0.54) | DPP4CYP2D6DPP7DPP9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921917-B1 | FUSED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK SHARP & DOHME (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2007024993-A2 | FUSED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2007-03-01 | — | — | WO | disclosed |