Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 4/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2432692 | 0.93 | TSHR (0.43) | TSHREPHX1CES2LMNATHRB | |
| SCHEMBL10427135 | 0.92 | TSHR (0.42) | TSHREPHX1THRB | |
| SCHEMBL10427162 | 0.88 | TSHR (0.42) | TSHREPHX1THRB | |
| SCHEMBL671675 | 0.84 | TSHR (0.45) | TSHRTHRB | |
| SCHEMBL8424510 | 0.81 | EPHX1 (0.55) | EPHX1CES2LMNAMAPTTHRB | |
| SCHEMBL673042 | 0.80 | TSHR (0.41) | TSHRTHRB | |
| SCHEMBL8426321 | 0.80 | EPHX1 (0.53) | TSHREPHX1CES2LMNAMAPT | |
| SCHEMBL1695697 | 0.79 | TSHR (0.44) | TSHRTHRB | |
| SCHEMBL28833506 | 0.78 | TSHR (0.42) | TSHREPHX1CES2LMNAMAPT | |
| SCHEMBL10624263 | 0.78 | EPHX1 (0.51) | TSHREPHX1CES2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100911-A1 | RESIN COMPOSITIONS, AND OPTICAL LENS PREPARED THEREBY | DOOSAN CORPORATION ELECTRO-MATERIALS BG (KR) | 2002-12-19 | — | — | WO | disclosed |