Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427298 | 1.00 | ITGB1 (0.51) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5701056 | 0.95 | ITGB1 (0.49) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5701054 | 0.95 | ITGB1 (0.49) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL7645582 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL7645576 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700984 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700989 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700993 | 0.91 | ITGB1 (0.51) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700996 | 0.91 | ITGB1 (0.51) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| Water SCHEMBL7651150 | 0.91 | ITGB1 (0.51) | ITGB1ITGA4ITGB7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | claimed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |