Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7647966 | 0.90 | F2 (0.49) | F2 | |
| SCHEMBL6745716 | 0.85 | F2 (0.60) | F2 | |
| SCHEMBL6856733 | 0.82 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL6745713 | 0.80 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL7648206 | 0.80 | F2 (0.45) | LMNAF2 | |
| SCHEMBL7647872 | 0.79 | F2 (0.49) | F2 | |
| Hydrochloric Acid SCHEMBL6927585 | 0.77 | F2 (0.63) | F2 | |
| Hydrochloric Acid SCHEMBL6749548 | 0.77 | F2 (0.42) | F2 | |
| Hydrochloric Acid SCHEMBL7645850 | 0.76 | F2 (0.44) | F2 | |
| Hydrochloric Acid SCHEMBL6747652 | 0.74 | F2 (0.69) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944590-B1 | AMINOGUANIDINES AND ALKOXYGUANIDINES AS PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-03-20 | — | — | EP | claimed |