Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641160 | 0.72 | USP2 (0.51) | HPGDKMT2APOLBUSP2NPC1 | |
| SCHEMBL14903555 | 0.70 | HPGD (0.49) | HPGDKMT2APOLBUSP2NPC1 | |
| SCHEMBL28861067 | 0.70 | NPC1 (0.45) | HPGDKMT2APOLBUSP2NPC1 | |
| SCHEMBL5789698 | 0.69 | KMT2A (0.43) | HPGDKMT2APOLBUSP2NPC1 | |
| SCHEMBL8936884 | 0.67 | USP2 (0.50) | HPGDKMT2APOLBUSP2NPC1 | |
| SCHEMBL8007043 | 0.67 | KMT2A (0.41) | HPGDKMT2APOLBUSP2NPC1 | |
| SCHEMBL5788912 | 0.67 | KMT2A (0.41) | HPGDKMT2APOLBUSP2NPC1 | |
| SCHEMBL7647778 | 0.67 | HPGD (0.43) | HPGDKMT2APOLBUSP2NPC1 | |
| SCHEMBL7619178 | 0.66 | CA12 (0.46) | KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7898666 | 0.66 | HPGD (0.48) | HPGDKMT2APOLBUSP2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376571-B1 | A (ALKYL)PHENYL ACRYLATE | DSM N.V. (NL) | 2002-04-23 | — | — | US | disclosed |