⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16134933 | 0.75 | — | — | |
| SCHEMBL17675846 | 0.71 | — | — | |
| SCHEMBL17675841 | 0.69 | — | — | |
| SCHEMBL910214 | 0.69 | — | — | |
| SCHEMBL11503254 | 0.67 | — | — | |
| SCHEMBL17676014 | 0.67 | — | — | |
| SCHEMBL23993499 | 0.67 | — | — | |
| SCHEMBL917482 | 0.67 | — | — | |
| SCHEMBL4154166 | 0.67 | — | — | |
| SCHEMBL22804028 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451829-B2 | ANTIALLERGENS, ANTIHISTAMINE | SIRCAR JAGADISH C (US) | 2002-09-17 | — | — | US | disclosed |
| US-20020010343-A1 | Compounds having IgE affecting properties | SIRCAR JAGADISH C (US) | 2002-01-24 | — | — | US | disclosed |
| US-6271390-B1 | Suppression of the IgE-dependent allergic response by benzimidazole analogs | AVANIR PHARMACEUTICALS | 2001-08-07 | — | — | US | disclosed |
| EP-0565826-B1 | Process for the preparation of substituted or unsubstituted chloromethylcyclopropane or bromomethylcyclopropane | HUELS CHEMISCHE WERKE AG (DE) | 1996-04-24 | — | — | EP | disclosed |
| EP-0565826-A1 | Process for the preparation of substituted or unsubstituted chloromethylcyclopropane or bromomethylcyclopropane | HÜLS AKTIENGESELLSCHAFT (DE) | 1993-10-20 | — | — | EP | disclosed |