Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.47 |
| ▸ | CHRNG | P07510 | 2/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CHRND | Q07001 | 2/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650861 | 0.89 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3PARP1 | |
| SCHEMBL11654173 | 0.86 | CHRM2 (0.45) | CHRM2CHRM4CHRM1CHRM3PARP1 | |
| SCHEMBL29764528 | 0.86 | PARP1 (0.61) | CHRM2CHRM4CHRM1CHRM3PARP1 | |
| SCHEMBL388521 | 0.86 | PARP1 (0.61) | CHRM2CHRM4CHRM1CHRM3PARP1 | |
| SCHEMBL11483394 | 0.82 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3PARP1 | |
| Sulfur Dioxide SCHEMBL28133474 | 0.81 | PARP1 (0.55) | CHRM2CHRM4CHRM1CHRM3PARP1 | |
| SCHEMBL27983665 | 0.81 | F2 (0.65) | PARP1ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8009083 | 0.80 | PARP1 (0.50) | CHRM2CHRM4CHRM1CHRM3PARP1 | |
| SCHEMBL11654653 | 0.80 | SLC6A2 (0.44) | CHRM2CHRM4CHRM1CHRM3PARP1 | |
| SCHEMBL16935937 | 0.80 | PARP1 (0.53) | CHRM2CHRM4CHRM1CHRM3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |