Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993141 | 1.00 | GNRHR (0.71) | GNRHRCYP3A4 | |
| SCHEMBL7994589 | 0.95 | GNRHR (0.69) | GNRHRCYP3A4 | |
| SCHEMBL7643850 | 0.93 | GNRHR (0.66) | GNRHRCYP3A4 | |
| Trifluoroacetic Acid SCHEMBL7643853 | 0.92 | GNRHR (0.66) | GNRHRCYP3A4 | |
| SCHEMBL7638040 | 0.89 | GNRHR (0.81) | GNRHRCYP3A4 | |
| Trifluoroacetic Acid SCHEMBL7603057 | 0.86 | GNRHR (0.67) | GNRHRCYP3A4 | |
| SCHEMBL7990680 | 0.86 | GNRHR (0.54) | GNRHRCYP3A4 | |
| SCHEMBL7990677 | 0.86 | GNRHR (0.54) | GNRHRCYP3A4 | |
| SCHEMBL7645090 | 0.81 | GNRHR (0.55) | GNRHRCYP3A4 | |
| SCHEMBL1535413 | 0.80 | GNRHR (0.81) | GNRHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165075-A4 | 6-AZAINDOLE COMPOUNDS AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2002-04-10 | — | — | EP | disclosed |
| EP-1165075-A1 | 6-AZAINDOLE COMPOUNDS AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6180642-B1 | SEXUAL DISORDERS; CONTRACEPTIVES | MERCK & CO., INC. | 2001-01-30 | — | — | US | disclosed |
| WO-2000053180-A1 | 6-AZAINDOLE COMPOUNDS AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 2000-09-14 | — | — | WO | disclosed |