Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286874 | 0.78 | TRPV1 (0.85) | TRPV1CYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL31010737 | 0.78 | TRPV1 (0.85) | TRPV1CYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL1286875 | 0.78 | TRPV1 (0.85) | TRPV1CYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL27205211 | 0.77 | TRPV1 (0.88) | TRPV1CYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL1586354 | 0.77 | TRPV1 (0.88) | TRPV1CYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL17859843 | 0.76 | TSHR (0.51) | CYP3A4LMNAGAA | |
| SCHEMBL12634829 | 0.76 | TRPV1 (0.71) | TRPV1CYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL6418721 | 0.76 | TSHR (0.56) | CYP3A4HPGDSMN1; SMN2GAA | |
| SCHEMBL10543855 | 0.75 | TRPV1 (0.84) | TRPV1CYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL10407917 | 0.75 | TRPV1 (0.84) | TRPV1CYP1A2CYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006449-A1 | Method of treatment of warts and moles | TERRY JAMES M (US) | 2002-01-17 | — | — | US | disclosed |
| US-6235788-B1 | Method for treating pre-malignant basal and squamous cell lesions of the epithelium | HEMAWAY PRODUCTS, L.C. | 2001-05-22 | — | — | US | disclosed |