Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 18/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 6/20 | 0.53 |
| ▸ | HTR3B | O95264 | 6/20 | 0.53 |
| ▸ | HTR3A | P46098 | 6/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 6/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059474 | 1.00 | CHRNA7 (0.53) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7063241 | 0.88 | CHRNA7 (0.56) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7596108 | 0.88 | CHRNA7 (0.56) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7059476 | 0.87 | CHRNA7 (0.56) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7059660 | 0.87 | CHRNA7 (0.50) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7061972 | 0.86 | CHRNA7 (0.57) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7063411 | 0.86 | CHRNA7 (0.59) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7060876 | 0.86 | CHRNA7 (0.55) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7061053 | 0.86 | CHRNA7 (0.60) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7063377 | 0.86 | CHRNA7 (0.58) | CHRNA7HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492385-B2 | CENTRAL NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN COMPANY | 2002-12-10 | — | — | US | disclosed |