Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | CA9 | Q16790 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825460 | 0.92 | CA12 (0.64) | CA12CA1CA9MAPTMEN1 | |
| SCHEMBL3823460 | 0.88 | CA12 (0.60) | CA12CA1CA9MAPTMEN1 | |
| SCHEMBL19288904 | 0.87 | CA12 (0.50) | CA12CA1CA9MAPTMEN1 | |
| SCHEMBL17357518 | 0.86 | CA12 (0.58) | CA12CA1CA9MAPTMEN1 | |
| SCHEMBL470906 | 0.84 | CA12 (0.57) | CA12CA1CA9MAPTMEN1 | |
| SCHEMBL30541768 | 0.84 | CA12 (0.57) | CA12CA1CA9MAPTMEN1 | |
| SCHEMBL21125695 | 0.84 | CA12 (0.47) | CA12CA1CA9MAPTMEN1 | |
| SCHEMBL25882213 | 0.83 | CA12 (0.56) | CA12CA1CA9MAPTMEN1 | |
| SCHEMBL3822410 | 0.83 | CYP3A4 (0.49) | CA12CA1CA9MAPTMEN1 | |
| SCHEMBL28406921 | 0.82 | CA12 (0.55) | CA12CA1CA9MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837851-B1 | FLUORINATED PHENANTHRENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-05-29 | — | — | EP | disclosed |
| US-5888422-A | Fluorinated phenanthrene derivatives and their use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-30 | — | — | US | disclosed |
| EP-0837851-A1 | FLUORINATED PHENANTHRENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-29 | — | — | EP | disclosed |
| EP-0743971-B1 | PHENANTHRIDINE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002247-A1 | FLUORINATED PHENANTHRENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-23 | — | — | WO | disclosed |
| EP-0743971-A1 | PHENANTHRIDINE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021227-A1 | PHENANTHRIDINE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-10 | — | — | WO | disclosed |