Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 7/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650759 | 1.00 | ITGB1 (0.46) | ITGB1ITGA4ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5700989 | 0.93 | ITGB1 (0.51) | ITGB1ITGA4ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5700984 | 0.93 | ITGB1 (0.51) | ITGB1ITGA4ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7652570 | 0.93 | KMT2A (0.42) | ITGB1ITGA4ALDH1A1MAPTL3MBTL1 | |
| Water SCHEMBL7651150 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5700996 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5700993 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4ALDH1A1MAPTL3MBTL1 | |
| Water SCHEMBL7651153 | 0.92 | ITGB1 (0.51) | ITGB1ITGA4ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7646191 | 0.92 | ITGB1 (0.45) | ITGB1ITGA4MAPTKMT2AMEN1 | |
| SCHEMBL7646186 | 0.92 | ITGB1 (0.45) | ITGB1ITGA4MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |