Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670505 | 0.85 | DAO (0.36) | DAOBRS3ALDH1A1HPGDKDM4E | |
| SCHEMBL4670507 | 0.85 | DAO (0.36) | DAOBRS3ALDH1A1HPGDKDM4E | |
| SCHEMBL753017 | 0.80 | CA12 (0.39) | DAOBRS3ALDH1A1HPGDKDM4E | |
| SCHEMBL752766 | 0.75 | DAO (0.41) | DAOBRS3ALDH1A1HPGDKMT2A | |
| SCHEMBL7188309 | 0.72 | HAO1 (0.39) | DAOBRS3ALDH1A1KDM4EEGFR | |
| SCHEMBL4680678 | 0.71 | HCAR2 (0.38) | DAOLMNA | |
| SCHEMBL4680681 | 0.71 | HCAR2 (0.38) | DAOLMNA | |
| SCHEMBL4676895 | 0.71 | SRD5A2 (0.38) | DAOBRS3ALDH1A1HPGDKDM4E | |
| SCHEMBL4676889 | 0.71 | SRD5A2 (0.38) | DAOBRS3ALDH1A1HPGDKDM4E | |
| SCHEMBL4676715 | 0.71 | ITGB1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |