Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.58 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750572 | 0.88 | F2 (0.62) | F2CTRCPRSS2F10 | |
| SCHEMBL6927837 | 0.86 | F2 (0.57) | F2CTRCPRSS2F10 | |
| SCHEMBL6929024 | 0.80 | F2 (0.51) | F2CTRCPRSS2F10 | |
| Hydrochloric Acid SCHEMBL7649325 | 0.79 | F2 (0.55) | F2CTRCPRSS2F10 | |
| SCHEMBL6747814 | 0.79 | F2 (0.72) | F2CTRCPRSS2 | |
| SCHEMBL14878176 | 0.77 | F2 (0.66) | F2CTRCPRSS2 | |
| SCHEMBL6749564 | 0.77 | F2 (0.66) | F2CTRCPRSS2 | |
| SCHEMBL5675805 | 0.76 | F2 (0.68) | F2CTRCPRSS2 | |
| SCHEMBL6748096 | 0.76 | F2 (0.68) | F2CTRCPRSS2 | |
| SCHEMBL5673644 | 0.75 | F2 (0.70) | F2CTRCPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944590-B1 | AMINOGUANIDINES AND ALKOXYGUANIDINES AS PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-03-20 | — | — | EP | disclosed |