Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7651597 | 0.99 | F2 (0.48) | F2KMT2AALDH1A1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL7650554 | 0.88 | F2 (0.45) | F2SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL6746007 | 0.87 | F2 (0.49) | F2 | |
| Hydrochloric Acid SCHEMBL7650543 | 0.87 | F2 (0.47) | F2 | |
| SCHEMBL7653398 | 0.86 | F2 (0.46) | F2KMT2AALDH1A1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL7647598 | 0.86 | F2 (0.47) | F2 | |
| Hydrochloric Acid SCHEMBL7650074 | 0.86 | F2 (0.46) | F2KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7649302 | 0.85 | F2 (0.46) | F2KMT2AALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL7647673 | 0.84 | F2 (0.44) | F2KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7859473 | 0.84 | F2 (0.45) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944590-B1 | AMINOGUANIDINES AND ALKOXYGUANIDINES AS PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-03-20 | — | — | EP | claimed |