Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.58 |
| ▸ | FAAH | O00519 | 3/20 | 0.56 |
| ▸ | CES1 | P23141 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19452424 | 0.94 | HDAC1 (0.67) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL8790943 | 0.88 | MAPT (0.66) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL11578613 | 0.86 | MAPT (0.69) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL26927562 | 0.86 | MAPT (0.63) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL10623470 | 0.86 | MAPT (0.69) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL7655514 | 0.86 | MAPT (0.69) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL13498527 | 0.86 | MAPT (0.63) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL29086538 | 0.85 | TDP1 (0.73) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL117432 | 0.85 | MAPT (0.61) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL6957940 | 0.85 | MAPT (0.61) | MAPTRXFP1HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |
| US-4156764-A | Poly(hydroxy) telechelic styrene polymer process | GENERAL ELECTRIC COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4146697-A | POLY(ORGANOSILOXY) TELECHELIC STYRENE POLYMER PROCESS | GENERAL ELECTRIC COMPANY (US) | 1979-03-27 | — | — | US | disclosed |