SCHEMBL765166

SCHEMBL765166

COC(=O)C1C[C@@H](NC(=O)c2cc3cc(C)ccc3[nH]2)[C@H](NC(=O)c2nc3c(s2)CN(C)CC3)C1

nearest known ligand 0.73

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.73
F2 P00734 5/20 0.66
PLAT P00750 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL765165 0.94 F10 (0.74) F10F2
SCHEMBL763946 0.94 F10 (0.78) F10F2
SCHEMBL763866 0.93 F10 (0.74) F10F2
SCHEMBL12631721 0.91 F10 (0.88) F10F2PLAT
SCHEMBL11888234 0.91 F10 (0.76) F10F2
SCHEMBL765123 0.91 F10 (0.76) F10F2
Hydrochloric Acid SCHEMBL4083773 0.91 F10 (0.86) F10F2PLAT
Hydrochloric Acid SCHEMBL10476746 0.91 F10 (0.86) F10F2PLAT
Hydrochloric Acid SCHEMBL4083771 0.91 F10 (0.86) F10F2PLAT
SCHEMBL10279468 0.90 F10 (0.85) F10F2PLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1270557-B1 ETHYLENEDIAMINE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2012-07-25 EP disclosed
EP-2431370-A1 Monoacylated 1,2-diaminocycloalkanes DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2012-03-21 EP disclosed