Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 5/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL764482 | 0.84 | BDKRB1 (0.38) | BDKRB1KDM4EMAPT | |
| SCHEMBL13904296 | 0.78 | BDKRB1 (0.49) | BDKRB1SUCNR1CNR1 | |
| SCHEMBL764412 | 0.78 | BDKRB1 (0.53) | BDKRB1 | |
| SCHEMBL13904097 | 0.76 | BDKRB1 (0.49) | BDKRB1NR3C1CNR1 | |
| SCHEMBL764431 | 0.76 | BDKRB1 (0.49) | BDKRB1LPAR1LPAR5CNR1 | |
| SCHEMBL10121503 | 0.76 | BDKRB1 (0.51) | BDKRB1KDM4EMAPT | |
| SCHEMBL2549218 | 0.76 | BDKRB1 (0.49) | BDKRB1NR3C1CNR1 | |
| SCHEMBL765154 | 0.76 | BDKRB1 (0.49) | BDKRB1CNR1 | |
| SCHEMBL764466 | 0.76 | BDKRB1 (0.51) | BDKRB1CNR1MAPT | |
| SCHEMBL764445 | 0.76 | BDKRB1 (0.47) | BDKRB1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |